Gene description for CD40LG
Gene name CD40 ligand
Gene symbol CD40LG
Other names/aliases CD154
CD40L
HIGM1
IGM
IMD3
T-BAM
TNFSF5
TRAP
gp39
hCD40L
Species Homo sapiens
 Experiment description of studies that identified CD40LG in Chronic lymphocytic leukemia cells

1
Experiment ID902
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method FACS
PubMed ID 26100252   
OrganismHomo sapiens
Experiment descriptionExosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
AuthorsPaggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E.
Journal name Blood
Publication year2015
SampleChronic lymphocytic leukemia cells
Sample nameMEC-1
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.15-1.17 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
FACS
Western blotting
EV-TRACK EV150015: EV-METRIC:22%, 44%

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